Posted September 20, 2013
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For me it usually goes in this order:
1. Antialiasing (MSAA, CSAA etc.). I usually disable this altogether, if I am not happy with the framerate. I can spot the difference, but IMHO the visual change is not big enough considering the big performance impact that antialising can many times have.
2. Motion blur. In fact, I many times prefer this off anyway, even if it doesn't affect framerate.
3. Any other oddball ones which have a big hit, but I can't really see any visual difference. Like that übersampling option in The Witcher 2, what the heck is that anyway?
4. Resolution. I usually rather lower the resolution from 1920x1080 to 1366x768 or even 1280x720, than touching rest of the settings.
I always take off motion blur and depth of field, I really hate those two settings.