Senteria: It is very possible. It's a complicated process where you have to go through a lot of steps in order to get it all to work. Now my ps2 has a modchip which allows me to run back up dvd's, ntsc, etc. Basically you need to have a way to install files to your memory card to mod your ps2 that way. Apparantly you can even connect the ps2 to the computer to play backups directly from the computer. I am really happy. Now my ps2 will last a lot longer when I don't have to use the laser.
liquidsnakehpks: while your laser is safe now but its not a 100% thing the ps2 will last longer , its known fact that modchips in ps2 tend to heat the system more and cause burnout of the capacitors etc in the long run
Yeah, I've read how Sony booby trapped the PS2's custom DVD drive to die an early death if such a thing is installed. Such things made sense at one point but parts are getting ever rarer and there are now other alternatives.
Dzsono: Have you considered emulation? There are some sweet graphical options available that make it superior to playing on your PS2!
100% compatibility on real hardware is nice. The ability to run ~80% of game from harddrive is also pretty sweet and the picture looks reasonable with certain inexpensive Chinese upscalers/ deinterlacers.